Washington University, USA
Helen McNeill
The overall goal of research in the McNeill lab is to understand how tissue growth and tissue organization are coordinately regulated during normal development, and how loss of this control leads to human disease. her group investigates how these processes are regulated using both Drosophila and mouse genetics for in vivo analysis, as well as tissue culture and organoid approaches. The Hippo pathway is a highly conserved signaling pathway that regulates proliferation and apoptosis via control of the activity of the transcriptional co-activators Yorkie/YAP.